![]() ![]() Peduncular hallucinosis is attributed to a range of various pathologies such as vascular and infectious midbrain, pontine and thalamic lesions, local subarachnoid hemorrhage, compression by tumors, basilar migraine, basilar vascular hypoplasia, and following regional surgical or angiographic interventions. However, some people experience agitation and delusion and mistake their hallucinations for reality. In most cases, people are aware that the hallucinations are not real. Peduncular hallucinosis has been described as a “release phenomenon” due to damage to the ascending reticular activating system, which is supported by the sleep disturbance characteristic of this syndrome. ![]() Most patients exhibit abnormal sleep patterns characterized by insomnia and daytime drowsiness. Lilliputian hallucinations (also called Alice in Wonderland syndrome), hallucinations in which people or animals appear smaller than they would be in real life, are common in cases of peduncular hallucinosis. The hallucinations are normally colorful, vivid images that occur during wakefulness, predominantly at night. Lhermitte provided a full account of his work in this area in his book "Les hallucinations: clinique et physiopathologie," which was published in Paris in 1951 by Doin publishing.Ĭontemporary researchers, with access to new technologies in medical brain imaging, have confirmed the brain localization of these unusual hallucinations. The accumulation of additional cases by Lhermitte and by others influenced academic medical debate about hallucinations and about behavioral neurology. After other similar case studies were published, this syndrome was labeled "peduncular hallucinosis." In 1922, the French neurologist Jean Lhermitte documented the case of a patient who was experiencing visual hallucinations that were suggestive of localized damage to the midbrain and pons. Because the content of the hallucinations is never exceptionally bizarre, patients can rarely distinguish between the hallucinations and reality. Unlike some other kinds of hallucinations, the hallucinations that patients with PH experience are very realistic, and often involve people and environments that are familiar to the affected individuals. Peduncular hallucinosis ( PH) is a rare neurological phenomenon that causes vivid visual hallucinations that typically occur in dark environments and last for several minutes. Medical condition Peduncular hallucinosis ![]()
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